肝窦内皮细胞在非酒精性脂肪性肝病中的研究进展

Research progress of liver sinusoidal endothelial cells in nonalcoholic fatty liver disease

非酒精性脂肪肝性肝病(NAFLD)在世界范围内广泛流行,是非常严重的公共卫生问题,目前尚无有效的药物治疗措施。肝窦内皮细胞(LSECs)是肝脏中占比最大的非实质细胞,但目前LSECs在NAFLD中发挥的作用尚不明确。现就近年LSECs在NAFLD中相关研究进展进行综述,以期为后续的研究提供一定的参考。

Non-alcoholic fatty liver disease(NAFLD)is widespread worldwide and thereby a very serious public health problem.There are currently no effective drug treatment measures.Liver sinusoidal endothelial cells(LSECs)are the most abundant non-parenchymal cells in the liver;however,it is still not clear what role LSECs play in NAFLD.This article reviews the research progress of LSECs in NAFLD in recent years in order to provide some reference for subsequent research.