摘要
The adenosine deaminase acting on RNA(ADAR)protein family was well characterized as RNA editing enzymes converting adenosines to inosines(A-to-l)in dsRNA structures.They share a homologous structure including the dsRNA-binding domain and the deaminase domain.ADAR1 function as the primary editing enzyme for A-to-l mutation because of its higher and ubiquitous expression compared to ADAR2 and ADAR3 in eukaryotes.
基金
This work was supported by the Foundation for Studying Abroadfrom the ChinaScholarship Counc(ilNo.201906210477)
the High-level University Construction Fund of Guangdong Province(China)(No.06-410-2106,154,06-410-2106,153,06-410-2107,229)
the Yunnan Digestive Endoscopy Clinical Medical Center Foundation for Health Commission of Yunnan Province(China)(No.2021LCZXXFXH018 of 2X2019-01-02)
the fund of Guangdong-Hongkong-Macao Joint Laboratory of Respiratory Infectious Disease for Dr Wenjie Chen(No.GHMJLRID-Z-202113).
