BISAP-O联合剩余碱对急性胰腺炎严重程度的早期评估价值

The Early Evaluation Value of BISAP-O Combined with Residual Alkali on the Severity of Acute Pancreatitis

目的探讨床旁严重度指数与肥胖指数(BISAP-O)联合剩余碱(BE)对急性胰腺炎(AP)严重程度的早期评估价值。方法选取2021年10月-2022年9月丰城市人民医院收治的AP患者84例(轻症64例,中度重症10例,重症10例),并将患者按预后情况分为预后良好组(63例)与预后不良组(21例)。比较不同病情严重程度与不同预后患者BISAP-O、BE差异,并绘制受试者工作特征(ROC),计算曲线下面积(AUC),评估BISAP-O、BE联合检测预测AP病情严重程度与预后的价值。结果重症者BISAP-O高于中度重症、轻症者,BE水平低于中度重症、轻症者,且中度重症BISAP-O高于轻症者,BE水平低于轻症者,有统计学差异(P<0.05);预后不良者BISAP-O高于预后良好者,BE水平低于预后良好者,有统计学差异(P<0.05);BISAP-O、BE联合检测预测AP病情严重程度与预后的AUC均高于单一检测(P<0.05)。结论BISAP-O联合BE能够更准确地判断AP患者病情严重程度,更好地预测患者预后情况,指导临床治疗。

Objective To explore the early evaluation value of bedside severity index combined with obesity index(BISAP-O)and residual alkali(BE)in the severity of acute pancreatitis(AP).Methods From October 2021 to September 2022,84 AP patients(64 mild cases,10 moderate severe cases,10 severe cases)were selected and divided into two groups according to the prognosis:good prognosis group(63 cases)and poor prognosis group(21 cases).The differences of BISAP-O and BE in patients with different severity and prognosis were compared,and the subjects'work characteristics(ROC)were drawn,and the area under the curve(AUC)was calculated to evaluate the value of BISAP-O and BE combined detection in predicting the severity and prognosis of AP.Results BISAP-O in severe patients was higher than that in moderate severe and mild patients,BE level was lower than that in moderate severe and mild patients,and BISAP-O in moderate severe patients was higher than that in mild patients,and BE level was lower than that in mild patients,with statistical difference(P<0.05);BISAP-O in patients with poor prognosis was higher than that in patients with good prognosis,and BE level was lower than that in patients with good prognosis(P<0.05);the AUC of BISAP-O and BE combined detection in predicting the severity and prognosis of AP was higher than that of single detection(P<0.05).Conclusion BISAP-O combined with BE can more accurately judge the severity of patients with AP,better predict the prognosis of patients,and guide treatment.