儿童青光眼角膜改变研究进展

Research progress of corneal changes in childhood glaucoma

儿童青光眼是一类在儿童期发生的因病理性眼内压升高导致视神经受损的疾病,常常导致患儿视力显著下降。由于儿童角膜的可塑性强,角膜改变是儿童青光眼不同于成人青光眼的至关重要的一点。角膜改变不仅是儿童青光眼诊断要点,与患儿视力预后也有重要关系。本文从不同类型儿童青光眼的常见角膜改变、角膜地形及角膜生物力学等角膜特殊改变的检测、角膜改变对诊断及预后的临床价值等方面的最新进展进行综述,以期为临床工作提供思路。

Childhood glaucoma is a kind of disease that occurs in childhood and characterized by retinal nerve injury due to pathologically increased intraocular pressure,which can cause significant visual loss.Corneal changes are crucial points that different from adult glaucoma because of the strong plasticity of children’s cornea.Corneal changes are not only crucial for diagnosis of childhood glaucoma,but also related to visual prognosis.In this paper,the common corneal changes,corneal topography and biomechanical detection,and the clinical value of corneal changes in diagnosis and prognosis of glaucoma in children were reviewed.