内陆山区务农人员创伤弧菌感染报告1例

Vibrio vulnificus infection in a farmer from inland mountainous areas:one case report

创伤弧菌是一种革兰阴性弯曲杆状细菌,存在于温暖的海水中,属嗜盐弧菌群。创伤弧菌可引起坏死性筋膜炎,是一种罕见但致命的临床急症,早期很难准确诊断。从患者血、渗出液、水疱和脑脊液中分离出创伤弧菌,是临床诊断该菌感染的金标准。创伤弧菌感染主要临床表现包括急性发热、寒战、出血性大疱性皮损和脓毒性休克,应立即予以适当的抗菌药物治疗,尽早手术干预。本文就1例创伤弧菌感染病例进行报告,旨在提高临床对非沿海地区创伤弧菌感染的认识,做到早诊断、早治疗。

Vibrio vulnificus(V.vulnificus)is a Gram-negative,curved rod-shaped bacterium which exists in warm seawater and belongs to Halophilic vibrio.V.vulnificus can cause necrotizing fasciitis,a rare but fatal clinical emergency that is difficult to diagnose accurately in the early stages.V.vulnificus can be isolated from patient’s blood,exudate,blisters and cerebrospinal fluid,which is the gold standard for clinical diagnosis of the infection.The main clinical manifestations of V.vulnificus infection included acute fever,chills,hemorrhagic bullous skin lesions,and septic shock.Appropriate antimicrobial therapy should be conducted immediately and early surgical intervention is necessary.This article reports a case of V.vulnificus infection,aiming to improve the clinical understanding on V.vulnificus infection in non-coastal areas and to achieve early diagnosis and treatment.