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乳腺及女性生殖系统肿瘤的临床分子诊断应用 被引量:1

Clinical molecular diagnosis of breast and female reproductive system tumors
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摘要 乳腺及女性生殖系统肿瘤严重威胁着女性健康。随着分子诊断研究的不断深入,乳腺及女性生殖系统肿瘤的基因组改变被不断揭示,肿瘤的诊断与治疗模式也逐渐发生改变,分子靶点的检测已成为肿瘤管理的一部分,准确识别肿瘤的分子靶点在疾病的诊断、治疗、监测转移、预测复发和预后中发挥重要作用。本文就分子诊断对于乳腺及女性生殖系统肿瘤的风险评估、分子分型、靶向治疗、毒副作用、预后评价等相关内容做一简要论述。 The gynecological tumours such as Breast cancer or female reproductive system tumors are a serious threat to female health.With the development of molecular diagnosis,the genomic changes of gynecological tumours have been revealed continuously,and the diagnosis and treatment modes of tumors have gradually changed.The detection of molecular targets which potentially participated in the transformation or progress of disease has become an important section of the management of female reproductive tumors,and accurate identification of molecular targets of tumors plays an important role in disease diagnosis,monitoring of metastasis,prediction of recurrence and treatment.This review briefly discusses the risk assessment,molecular typing,targeted therapy,toxic and side effects,and prognosis evaluation of breast and female reproductive system tumors by molecular diagnosis.
作者 吴茜 王京伟 郑红云 童永清 Wu Qian;Wang Jingwei;Zheng Hongyun;Tong Yongqing(Clinical Molecular Diagnostics Institute,Renmin Hospital of Wuhan University,Wuhan 430060,China)
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2023年第4期334-340,共7页 Chinese Journal of Laboratory Medicine
关键词 泌尿生殖系统肿瘤 分子诊断技术 卵巢肿瘤 宫颈肿瘤 乳腺肿瘤 子宫内膜肿瘤 Urogenital neoplasms Molecular diagnostic techniques Ovarian neoplasms Cervical neoplasms Breast neoplasms Endometrial neoplasms
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