胰腺脂肪浸润与胰腺癌的相关性分析

Correlation between fatty pancreas disease and pancreatic cancer

目的:在经超声内镜行胰腺检查患者中评价胰腺脂肪浸润与胰腺癌的相关性。方法:回顾性收集我院2019年1月至2021年12月行超声内镜胰腺检查的患者年龄、性别、胰腺超声内镜检查结果、胰腺占位性病变穿刺结果及临床生化指标并进行统计学分析。结果:本研究共纳入1 070例患者,其中胰腺癌93例,占8.7%,胰腺脂肪浸润229例,占21.4%,单因素相关性分析显示:年龄、性别、胰腺脂肪浸润均与胰腺癌显著相关,总胆固醇与低密度脂蛋白与胰腺癌患者中的胰腺脂肪浸润显著相关。Logistics多因素回归分析显示:年龄、性别、胰腺脂肪浸润均为胰腺癌的独立危险因素。结论:胰腺脂肪浸润与胰腺癌显著相关并是其独立的危险因素。

Objective:To evaluate the correlation between fatty pancreas disease and pancreatic cancer in patients underwent endoscopic ultrasound(EUS)examination.Methods:The age,gender,results of EUS,pathological type and clinical biochemical indicators of patients who underwent EUS for pancreas from January 2019 to December 2021 were retrospectively collected and analyzed.Results:A total of 1070 patients were included in this study,including 93 cases of pancreatic cancer,accounting for 8.7%,and 229 cases of fatty pancreas disease,accounting for 21.4%.Univariate correlation analysis showed that age,gender,and fatty pancreas disease were significantly associated with pancreatic cancer.Total cholesterol and low-density lipoprotein were significantly associated with fatty pancreas disease in patients with pancreatic cancer.Logistics multivariate regression analysis showed that age,gender,and fatty pancreas disease were independent risk factors for pancreatic cancer.Conclusion:Fatty pancreas disease is significantly associated with pancreatic cancer and is an independent risk factor.