摘要
报道一例大剂量甲氨蝶呤控制病情后使用常规剂量TNF-α抑制剂维持治疗的关节病型银屑病患者,维持治疗3年后躯干及双下肢发疹,加用IL-17拮抗剂,皮损消退后停用TNF-α抑制剂,IL-17拮抗剂维持治疗8周,皮疹完全消退,关节症状无复发。
We reported a case of psoriatic arthritis using conventional dose of TNF-αinhibitor after controlling the disease with high dose methotrexate.After three years of maintenance therapy,the patient occurred skin lesions on the trunk and both lower limbs.The patient was treated with IL-17 inhibitor and TNF-αinhibitor until the lesion disappeared,IL-17 inhibitor monotherapy for 8 weeks,the lesions were completely subsided and no recurrence of joint symptoms.
作者
曹珊
孙勇虎
赵晴
刘红
张福仁
CAO Shan;SUN Yonghu;ZHAO Qing;LIU Hong;ZHANG Furen(Department of Dermatology,Shandong Provincial Hospital for Skin Diseases&Shandong Provincial Institute of Dermatology and Venereology,Shandong First Medical University&Shandong Academy of Medical Sciences,Jinan 250022,China)
出处
《中国麻风皮肤病杂志》
2023年第5期353-354,共2页
China Journal of Leprosy and Skin Diseases
基金
山东省皮肤性病学临床医学研究中心
山东第一医科大学学术提升计划(编号:2019LJ002)。
