氨甲环酸的不良反应及处理

Adverse reactions and management of tranexamic acid

近年来氨甲环酸在皮肤科的应用日益增加,该药以低剂量口服为主,安全性较好,最常见的不良反应是胃肠道不适和月经不规则。但长期系统应用氨甲环酸可导致多种不良反应,如血栓形成、肝肾功能损害、视力缺陷等。因此,长期服用氨甲环酸时需定期监测凝血功能、D-二聚体、肝肾功能等相关指标,争取及时发现并尽快处理药物不良反应,保证用药安全。

Tranexamic acid has been increasingly used in dermatology in recent years.The drug is mainly administrated orally at low doses with good safety,and the most common adverse reactions are gastrointestinal discomfort and menstrual irregularity.However,long-term systemic application of tranexamic acid can lead to a variety of adverse reactions,such as thrombosis,hepatic and kidney impairment,visual defects,etc.Therefore,regularly monitoring blood coagulation function,D-dimer,hepatic and kidney function and other related indicators is necessary when taking tranexamic acid for a long time,so as to detect and manage adverse reactions timely and ensure drug safety.