纤维支气管镜治疗小儿支原体肺炎合并肺不张的效果观察

Effect Observation of Fiberoptic Bronchoscopy in Treatment of Children with Mycoplasma Pneumonia Complicated with Atelectasis

目的:探讨纤维支气管镜治疗小儿支原体肺炎合并肺不张的效果。方法:选取2020年11月—2021年12月武县人民医院收治的98例小儿支原体肺炎并肺不张患儿作为研究对象,通过计算机抽签法分为研究组与参照组,各49例。参照组实施抗感染雾化治疗,研究组在参照组基础上实施纤维支气管镜治疗。比较两组治疗效果、血清炎性因子水平、肺复张情况、不良反应发生情况。结果:研究组治疗总有效率高于参照组,差异有统计学意义(P=0.019 5)。治疗前,两组白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、超敏C反应蛋白(hs-CRP)水平比较,差异无统计学意义(P>0.05);治疗后,研究组IL-6、TNF-α、hs-CRP水平低于参照组,差异有统计学意义(P=0.000)。研究组复张率高于参照组,差异有统计学意义(P=0.025)。两组不良反应发生率比较,差异无统计学意义(P=0.239)。结论:纤维支气管镜治疗小儿支原体肺炎合并肺不张的效果显著,可改善患儿血清炎性因子水平及肺不张症状,同时具有较高的安全性。

Objective:To explore the effect of fiberoptic bronchoscopy in the treatment of children with mycoplasma pneumonia complicated with atelectasis.Methods:A total of 98 children with mycoplasma pneumonia and atelectasis in Chengwu County People's Hospital from November 2020 to December 2021 were selected as study subjects.They were divided into study group and reference group by computer lottery method,with 49 cases in each group.The reference group was treated with anti-infection nebulization,and the study group was treated with fiberoptic bronchoscopy on the basis of the reference group.The treatment effect,serum inflammatory factor level,lung recruitment and adverse reactions of the two groups were compared.Results:The total effective rate of treatment in the study group was higher than that in the reference group,and the difference was statistically significant(P=0.0195).Before treatment,there was no significant difference in the levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and hypersensitivity C-reactive protein(hs-CRP)between the two groups(P>0.05).After treatment,the levels of IL-6,TNF-αand hs-CRP in the study group were lower than those in the reference group,and the differences were statistically significant(P=0.000).The recruitment rate in the study group was higher than that in the reference group,and the difference was statistically significant(P=0.025).There was no significant difference in the incidence of adverse reactions between the two groups(P=0.239).Conclusion:Fiberoptic bronchoscopy has a significant effect in the treatment of pediatric mycoplasma pneumonia complicated with atelectasis,which can improve the levels of serum inflammatory factors and atelectasis symptoms in children,and has a high safety.