苯磺酸氨氯地平片治疗社区高血压的效果分析

Effect Analysis of Amlodipine Besylate Tablets in Treatment of Hypertension in Community

目的:探讨苯磺酸氨氯地平片治疗社区高血压的效果。方法:选取2021年2月—2022年2月武汉东湖新技术开发区花山街社区卫生服务中心收治的88例原发性高血压患者作为研究对象,依据随机数字表法分为研究组与常规组,各44例。常规组给予硝苯地平控释片治疗,研究组给予苯磺酸氨氯地平片治疗。比较两组临床疗效、血压水平、不良反应发生情况、生活质量。结果:研究组治疗总有效率高于常规组,差异有统计学意义(P=0.046)。用药前,两组舒张压、收缩压比较,差异无统计学意义(P>0.05);用药后,研究组舒张压、收缩压低于常规组,差异有统计学意义(P<0.05)。研究组不良反应发生率低于常规组,差异有统计学意义(P=0.026)。用药前,两组生理职能、情感职能、躯体疼痛、生理机能、精神健康、精力、社会功能、总体健康评分比较,差异无统计学意义(P>0.05);用药后,研究组各项生活质量评分均高于常规组,差异有统计学意义(P<0.05)。结论:苯磺酸氨氯地平片治疗社区高血压的效果显著,可降低患者收缩压、舒张压水平及不良反应发生率,提高患者生活质量。

Objective:To explore the effect of amlodipine besylate tablets in the treatment of hypertension in the community.Methods:From February 2021 to February 2022,88 patients with essential hypertension admitted to the Huashan Street Community Health Service Center of East Lake New Technology Development Zone in Wuhan were selected as the study subjects.They were divided into the study group and the conventional group according to the random number table method,with 44 cases in each group.The conventional group was treated with nifedipine controlled-release tablets,and the study group was treated with amlodipine besylate tablets.The clinical efficacy,blood pressure level,incidence of adverse reactions and quality of life in the two groups were compared.Results:The total effective rate of treatment in the study group was higher than that in the conventional group,and the difference was statistically significant(P=0.046).Before medication,there was no significant difference in diastolic blood pressure and systolic blood pressure between the two groups(P>0.05).After medication,diastolic blood pressure and systolic blood pressure in the study group were lower than those in the conventional group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the study group was lower than that in the conventional group,and the difference was statistically significant(P=0.026).Before medication,there were no significant differences in physiological function,emotional function,somatic pain,physiological functioning,mental health,energy,social function,and overall health scores between the two groups(P>0.05).After medication,the quality of life scores in the study group were higher than those in the conventional group,and the difference was statistically significant(P<0.05).Conclusion:Amlodipine besylate tablets have a significant effect in the treatment of hypertension in the community,it can reduce the level of systolic blood pressure,diastolic blood pressure and the incidence of adverse reactions in patients,and improve the quality of life of patients.