血塞通联合倍他司汀治疗后循环性缺血眩晕的效果分析

Effect Analysis of Xuesaitong Combined with Betahistine in Treatment of Posterior Circulation Ischemic Vertigo

目的:探讨血塞通联合倍他司汀治疗后循环性缺血眩晕的效果。方法:选取2020年1月—2021年10月南通市海门区海门港新区中心卫生院收治的80例后循环性缺血眩晕患者作为研究对象,使用随机数字表法分为联合组与常规组,各40例。常规组应用倍他司汀治疗,联合组在常规组基础上应用血塞通治疗。比较两组血液流变学指标、椎-基底动脉平均血流速度、治疗效果。结果:治疗前,两组血浆黏度、血小板黏附率、全血黏度比较,差异无统计学意义(P>0.05);治疗后,两组血浆黏度、血小板黏附率、全血黏度均低于治疗前,且联合组低于常规组,差异有统计学意义(P=0.000 0)。治疗前,两组右椎动脉、左椎动脉、基底动脉平均血流速度比较,差异无统计学意义(P>0.05);治疗后,两组右椎动脉、左椎动脉、基底动脉平均血流速度均高于治疗前,且联合组高于常规组,差异有统计学意义(P=0.000 0)。联合组治疗总有效率高于常规组,差异有统计学意义(P=0.013 2)。结论:血塞通联合倍他司汀治疗后循环性缺血眩晕的效果显著,能明显改善患者血液流变学指标,提升椎-基底动脉平均血流速度。

Objective:To explore the effect of Xuesaitong combined with betahistine in the treatment of posterior circulation ischemic vertigo.Methods:A total of 80 patients with posterior circulation ischemic vertigo who were admitted to Central Health Center of Haimen Port New District of Haimen District of Nantong City from January 2020 to October 2021 were selected as the study subjects.They were divided into conventional group and combined group according to random number table method,with 40 cases in each group.The conventional group was treated with betahistine alone,and the combined group was treated with Xuesaitong on the basis of conventional group.The blood rheological indexes,the average blood flow velocity of the vertebrobasilar artery,and the treatment effect of the two groups were compared.Results:Before treatment,there were no significant differences in plasma viscosity,platelet adhesion rate and whole blood viscosity between the two groups(P>0.05).After treatment,the plasma viscosity,platelet adhesion rate and whole blood viscosity in the two groups were lower than those before treatment,and the combined group was lower than the conventional group,and the difference was statistically significant(P=0.0000).Before treatment,there were no significant differences in the average blood flow velocity of the right vertebral artery,left vertebral artery and basilar artery between the two groups(P>0.05).After treatment,the average blood flow velocity of the right vertebral artery,left vertebral artery and basilar artery in the two groups was higher than that before treatment,and the combined group was higher than the conventional group,and the difference was statistically significant(P=0.0000).The overall response rate of treatment in the combined group was higher than that in the conventional group,and the difference was statistically significant(P=0.0132).Conclusion:The Xuesaitong combined with betahistine in the treatment of patients with posterior circulation ischemic vertigo has significant effect and can obvious improve blood rheological indexes and increase the average blood flow velocity of the vertebrobasilar artery.