深度肌松对乳腺癌改良根治术后疼痛影响分析

The effect of deep muscle relaxation on pain after modified radical mastectomy for breast cancer

目的观察深度肌松对乳腺癌改良根治术后疼痛的影响。方法选择潍坊医学院附属医院于2021年10月~2022年12月接收的乳腺癌根治术治疗的女性患者80例,随机分为观察组(深肌松PTC≤2)和对照组(浅肌松TOF=4)。应用视觉疼痛模拟评分法(VAS)评估患者术后疼痛程度,检测患者术前及术后血清IL-6及BK的水平。结果观察组术后VAS评分低于对照组(P<0.05)。观察组术后IL-6、BK水平低于对照组(P<0.05)。结论深度肌松应用于乳腺癌改良根治术麻醉效果较好,可显著减轻患者术后疼痛。

Objective To observe the effect of deep muscle relaxation on pain after modified radical mastectomy for breast cancer.Methods A total of 80 female patients treated with radical mastectomy for breast cancer from October 2021 to December 2022 were chosen in the Affiliated Hospital of Weifang Medical University and randomly divided them into two groups.The operation was done under deep muscle relaxation(post-tetanic count stimulation,PTC≤2)in the observation group,while the operation was done under superficial muscle relaxation(train of four stimulation,TOF=4)in the control group.Visual Analogue Scale(VAS)was used to score the degree of pain and to test the serum levels of IL-6 and BK before and after the surgery.Results The postoperative VAS score in the observation group was lower than that in the control group(P<0.05).The postoperative IL-6 and BK levels in the observation group were lower than those in the control group(P<0.05).Conclusion Deep muscle relaxation which is used in the modified radical mastectomy for breast cancer has better anesthetic effect and it can significantly reduce the postoperative pain for the patients.