Mutation N856K in spike reduces fusogenicity and infectivity of Omicron BA.1
摘要
Dear Editor,COVID-19 lung pathology is characterized by interstitial pneumonia with cell-cell fusion-induced syncytia and extensive tissue damage.1 The correlation between viral fusogenicity and pathogenicity has been reported in SARS-CoV-2 variants.2 Compared with the previous Delta or D614G variants,Omicron BA.1 has been proven to be less fusogenic and pathogenic.
基金
Beijing Municipal Science and Technology Commission(Z211100002521026).
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