掌跖脓疱病的治疗进展

Progress in the Treatment of Palmoplantar Pustulosis

掌跖脓疱病是一种慢性、复发性、炎症性皮肤病,好发于女性,以掌跖部出现对称性、无菌性脓疱为主要特征。这些病变通常会令患者感到痛苦,并显著降低生活质量,但目前尚无标准治疗方案。除传统外用药物、物理疗法及系统药物外,最近还出现了一些诸如生物制剂、小分子药物等新的治疗方法。本文检索了近年来国内外关于治疗掌跖脓疱病的文献,总结了传统的治疗方法,同时介绍了新的治疗方法,以期为医护人员提供参考。

Palmoplantar pustulosis is a chronic,recurrent,inflammatory skin disease characterized by symmetrical and sterile pustules on palms and soles,which is more common in women.The lesions are usually painful and remarkably decrease the quality of life,but there is no standard treatment plan at present.In addition to traditional external drugs,physical therapy and systemic drugs,some new treatment methods such as biological agents and small molecular drugs have recently emerged.We searched many papers published in recent years at home and abroad,summarized the traditional treatment methods,and introduced the new treatment methods.It is intended to provide a reference for medical workers.