老年高血压患者相关性衰弱的研究进展

Research progress on hypertension related frailty in the elderly

高血压是目前老年人中常见的慢性疾病,而衰弱是老年人的生理储备能力下降引起机体易损性升高、抗应激能力下降的非特异状态,在受到较小刺激时即可产生一系列临床负性事件。衰弱和高血压常于老年人群中同时存在,相关诊疗指南建议对于老年高血压患者在采用降压药物降压时也应开展衰弱状态评估,按照患者的生理情况开展降压治疗的风险和获益测评,这对于临床采取个性化降压治疗方案和确定降压目标、提高老年高血压的管理质量有一定益处。对于老年高血压患者衰弱的研究进展进行综述,以为其个性化治疗提供借鉴。

Hypertension is currently the most common chronic disease in the elderly,and frailty is a non-specific state in which vulnerability of the body increases and anti-stress ability decreases due to physiological reserve function decline.A series of clinical adverse events may occur in elderly people with frailty when there is a small stimulus.Frailty and hypertension often coexist in the elderly.Relevant guidelines for diagnosis and treatment recommend that elderly patients with hypertension should be evaluated for frailty when using antihypertensive drugs.The risks and benefits of antihypertensive treatment should be evaluated according to the patient′s physiological reserves,thereby helping to choose personalized antihypertensive treatment,determining appropriate antihypertensive goals,and improving the management of elderly hypertension.Herein,the research progress on hypertension related frailty in the elderly is reviewed to provide reference for personalized treatment of elderly patients with hypertension.