措施分类护理模式在急性髓系白血病缓解后化疗患者中的应用效果

Application effect of measure-classified nursing mode in patients with acute myeloid leukemia undergoing chemotherapy after remission

目的探究措施分类护理模式在急性髓系白血病缓解后化疗患者中的应用效果。方法本研究为随机对照试验。以2020年1月至2021年12月安阳市人民医院抽取的72例急性髓系白血病缓解后化疗患者作为研究对象,按照随机数字表法分为两组,各36例。对照组男22例、女14例,年龄(39.51±5.67)岁,采取基础护理模式;观察组男23例、女13例,年龄(39.46±5.39)岁,在对照组基础上增加措施分类护理。对比两组患者护理前后癌性疲乏量表(Cancer Fatigue Scale,CFS)、生活质量评分及不良反应发生率。采用t检验、χ^(2)检验。结果干预后,观察组躯体疲乏[(29.64±2.04)分]、认知疲乏[(35.88±1.75)分]、情感疲乏评分[(24.36±1.76)分]均低于对照组[(30.97±1.35)分、(36.91±2.52)分、(25.20±1.15)分],差异均有统计学意义(t=3.262、2.014、2.397,均P<0.05)。干预后,观察组躯体疼痛[(83.46±2.92)分]、生理职能[(82.21±2.78)分]、情感职能[(84.18±2.81)分]、生理功能[(83.14±2.74)分]、精神健康[(84.16±2.91)分]、精力[(85.13±2.87)分]、社会功能[(84.27±2.86)分]及总体健康评分[(85.13±2.87)分]均高于对照组[(81.81±2.77)分、(80.67±2.84)分、(82.61±2.66)分、(81.64±2.83)分、(82.63±2.87)分、(83.58±2.93)分、(82.71±2.65)分、(83.59±2.93)分],差异均有统计学意义(t=2.460、2.325、2.435、2.285、2.246、2.267、2.400、2.253,均P<0.05)。观察组不良反应发生率为8.33%(3/36),低于对照组27.78%(10/36),差异有统计学意义(χ^(2)=4.599,P=0.032)。结论针对急性髓系白血病缓解后化疗患者采取措施分类护理,可有效改善患者心理疲乏状态,提高生存质量,改善不良反应发生率,利于预后,值得临床推广借鉴。

Objective To explore the application effect of measure-classified nursing mode in patients with acute myeloid leukemia undergoing chemotherapy after remission.Methods It was a randomized controlled trial.A total of 72 patients with acute myeloid leukemia undergoing chemotherapy after remission were selected from The People's Hospital of Anyang City from January 2020 to December 2021 as the research subjects,and were divided into two groups by the random number table method with 36 cases in each group.In the control group,there were 22 males and 14 females,aged(39.51±5.67)years.In the observation group,there were 23 males and 13 females,aged(39.46±5.39)years.The control group received the basic nursing model,and the observation group added classified nursing measures on the basis of the control group.The scores of Cancer Fatigue Scale(CFS)and quality of life before and after nursing and incidence of adverse reactions were compared between the two groups.t test andχ^(2) test were used.Results After intervention,the scores of physical fatigue[(29.64±2.04)points],cognitive fatigue[(35.88±1.75)points],and emotional fatigue[(24.36±1.76)points]in the observation group were lower than those in the control group[(30.97±1.35)points,(36.91±2.52)points,and(25.20±1.15)points],with statistically significant differences(t=3.262,2.014,and 2.397;all P<0.05).After intervention,the scores of physical pain[(83.46±2.92)points],physiological role[(82.21±2.78)points],emotional role[(84.18±2.81)points],physiological function[(83.14±2.74)points],mental health[(84.16±2.91)points],energy[(85.13±2.87)points],social function[(84.27±2.86)points],and overall health[(85.13±2.87)points]in the observation group were higher than those in the control group[(81.81±2.77)points,(80.67±2.84)points,(82.61±2.66)points,(81.64±2.83)points,(82.63±2.87)points,(83.58±2.93)points,(82.71±2.65)points,and(83.59±2.93)points],with statistically significant differences(t=2.460,2.325,2.435,2.285,2.246,2.267,2.400,and 2.253;all P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group[8.33%(3/36)vs.27.78%(10/36)],with a statistically significant difference(χ^(2)=4.599,P=0.032).Conclusion Classified nursing measures for patients with acute myeloid leukemia undergoing chemotherapy after remission can effectively improve their mental fatigue,improve their quality of life,improve the incidence of adverse reactions,and is beneficial to the prognosis.