肠道菌群与糖尿病微血管病变的研究进展

Overview of the relationship between intestinal flora and diabetic microvascular diseases

DM微血管病变在高血糖刺激下损伤微动静脉和毛细血管,累及肾脏、视网膜、神经等,影响患者生活质量与预期寿命。肠道菌群影响机体物质代谢、能量吸收等,参与DM微血管病变。补充微生态制剂益生菌可能调整肠道菌群结构,影响DM微血管病变进展。本文综述肠道菌群与DM微血管病变的研究进展。

Diabetes mellitus(DM)microvascular diseases isa group of common complications that affect the quality of life and life expectancy of patientsby damaging arterioles and capillaries under the stimulation of hyperglycemia,involving kidneys,retina,nerves,etc. Intestinal flora affects the metabolism and energy absorption of the body,and participates in the occurrence of DM microvascular diseases. Supplementing probiotics can improve the intestinal microecology,and then affect the progression of DM and its microvascular disease. This article reviews the research progress of intestinal microflora and diabetic microangiopathy.