斑马鱼脊柱区的发育

Development of the spinal region in zebrafish

斑马鱼(Danio rerio)作为模式生物,有关它的研究不胜枚举,然而对其脊柱区发育的相关研究却相对较少。本文从中枢神经系统发育、骨骼发育、骨骼肌发育、相关结缔组织及脊柱区的运动5个方面对斑马鱼脊柱区的发育进行综述,以便进一步认识这一优良动物模型,并对其相关基础研究起到启示作用。

Zebrafish have been widely used to investigate various fields as a model organism,but relatively little attention has been focused on exploring development of its spinal region.Here,we review the development of the zebrafish spinal region from five aspects:the central nervous system(CNS),skeletal system,skeletal muscle system,associated connective tissue,and movement of the spinal region,to further our understanding of this excellent animal model and contribute to its basic research.