心肌梗死四项的指标水平在急性心肌梗死患者血中之联合表达

Value of cardiac troponin I,creatine kinase isoenzyme-MB myoglobin and B brain natriuretic peptide precursor in diagnosis of acute myocardial infarction

目的探讨全血中心肌肌钙蛋白I(cTnI),肌酸激酶同工酶-MB(CK-MB),肌红蛋白(Myo)和B型脑钠肽前体(NT-proBNP)的联合检测在急性心肌梗死诊断中的应用价值。方法选取河南省人民医院确诊为急性心肌梗死(AMI)的病人102例设为实验组,另外选取健康人102例,设为对照组。检测两组受试者全血中cTnI,Myo,CK-MB及NT-proBNP的表达,对比两组的结果,并对比联合检测和单项检测的结果。结果实验组的cTnI,Myo,CK-MB及NT-proBNP的表达均高于对照组(P<0.05),且这些指标的联合检测阳性率高于单项检测。结论急性心肌梗死的患者全血中cTnI,Myo,CK-MB及NT-proBNP的联合检测有利于提高疾病诊断的准确率,值得在临床推广。

Objective To explore the value of cardiac troponin I(cTnl),creatine kinase isoenzyme-MB(CK-MB),myoglobin(Myo)and B brain natriuretic peptide precursor(NT-proBNP)in the diagnosis of acute myocardial infarction.Methods 102 patients diagnosed with acute myocardial infarction(AMI)were selected as the experimental group,and 102 healthy patients were selected as the control group.The expression of cTnl,Myo,CK-MB and NT-proBNP in whole blood was compared the results and the results of the combined and individual tests.Results The expression of cTnI,Myo,CK-MB and NT-proBNP in the experimental group was higher than that in the control group(P<0.05),and the positive rate of these indexes was higher than that of the individual test.Conclusion The combined detection of cTnI,Myo,CK-MB and NT-proBNP in whole blood of patients with acute myocardial infarction is beneficial to improve the accuracy of disease diagnosis and should be worth popularizing in clinical practice.