百里醌在胰腺癌治疗中的作用

Role of thymoquinone in treatment of pancreatic cancer

胰腺癌是预后最差的癌症之一,其高转移率和化疗药物耐药性一直是困扰医学界的难题。目前关于百里醌对胰腺癌影响的研究受到了人们的广泛关注,其可以通过抑制癌细胞增殖、促进癌细胞凋亡、抑制侵袭与转移、增强化疗药物敏感性、抗炎等方面发挥对胰腺癌的抗癌作用。该综述简要介绍了国内外对两者关系的研究现状,为下一步的研究提供参考。

Pancreatic cancer is one of the cancers with the worst prognosis,and its high metastasis rate and resistance to chemotherapy drugs have always been the tough problems in the medical field.At present,the effect of thymoquinone on pancreatic cancer has attracted wide attention,and it can exert an antitumor effect in pancreatic cancer by inhibiting cancer cell proliferation,promoting cancer cell apoptosis,inhibiting invasion and metastasis,enhancing the sensitivity to chemotherapy drugs,and exerting an anti-inflammatory effect.This review briefly introduces the current research status of the association between thymoquinone and pancreatic cancer in China and globally,so as to provide a reference for subsequent research.