S-Detect技术与应变弹性成像对C-TI-RADS 4A类甲状腺结节的诊断价值

Diagnosis value of S-Detect technique and strain elastography for C-TI-RADS 4A thyroid nodules

目的评估S-Detect技术与应变弹性成像对C-TI-RADS 4A类甲状腺结节的再分类,探讨二者对C-TI-RADS 4A类甲状腺结节的诊断价值。方法选取2021年4月—2022年4月在南京医科大学第一附属医院超声诊断科常规超声检查报告为C-TI-RADS 4A类且有明确病理结果的87例患者共102个结节,应用三星S-Detect技术与应变弹性成像对结节辅助诊断重新分类,比较S-Detect技术、应变弹性成像及2种方法协助人工再分类诊断结果与病理结果的一致性,以及2种方法对C-TI-RADS 4A类结节的诊断效能。结果2种方法诊断结果与病理结果具有一致性,S-Detect技术与病理结果的一致性(Kappa=0.652,P<0.001)高于应变弹性成像(Kappa=0.381,P<0.001),2种方法协助人工再分类与病理结果的一致性(Kappa=0.510,P<0.001)介于二者之间,S-Detect技术和应变弹性成像对C-TI-RADS 4A类结节良恶性诊断的灵敏度、特异度、准确度分别为93.10%、70.45%、83.33%和62.07%、77.27%、68.63%。S-Detect技术诊断C-TI-RADS 4A类结节的灵敏度、准确度高于应变弹性成像(均P<0.05),而两者诊断的特异度比较差异无统计学意义(P>0.05)。结论S-Detect技术与应变弹性成像作为辅助性诊断方法,对C-TI-RADS 4A类结节的诊断与病理结果均具有一致性,且前者一致性高。

Objective Evaluate the reclassification of C-TI-RADS 4A thyroid nodules using S-Detect technology and strain elastography,and explore their diagnostic value for C-TI-RADS 4A thyroid nodules.Methods A total of 102 nodules were selected from 87 patients of C-TI-RADS 4A with clear-defined pathological results from April 2021 to April 2022 in the routine ultrasound examination of the First Affiliated Hospital of Nanjing Medical University.Samsung S-Detect technology and strain elastography were used to aid in the reclassification of nodules.The consistency between S-Detect technology,strain elastography,two methods to assist in manual reclassification diagnosis and pathological results was compared,as well as the diagnostic efficacy of the two methods for C-TI-RADS 4A type nodules.Results The diagnostic results of the two methods were consistent with the pathological results,the consistency between S-Detect technology and the pathological results(Kappa=0.652,P<0.001)was higher than that of strain elastography(Kappa=0.381,P<0.001),the consistency between the manual reclassification assisted by the two methods and the pathological results(Kappa=0.510,P<0.001)was between the two methods.The sensitivity,specificity and accuracy of S-Detect technology and strain elastography for the benign and malignant diagnosis of C-TI-RADS 4A nodules were 93.10%,70.45%,83.33%and 62.07%,77.27%and 68.63%,respectively.The sensitivity and accuracy of S-Detect technology in diagnosing C-TI-RADS 4A nodules was higher than that of strain elastography(all P<0.05),however,the specificity of the two methods was not statistically significant(P>0.05).Conclusion The S-Detect technique and strain elastography,as an assisted diagnostic method,have consistent diagnostic results of C-TI-RADS 4A type nodules with pathological results,and the S-Detect technique has high consistency.