新型冠状病毒感染对男性精液检测指标的影响

Effects of Novel Coronavirus Infection on Semen Indexes

目前新型冠状病毒感染的机制已经明确,男性生殖系统也可能是新型冠状病毒感染的目标。男性感染新型冠状病毒后,可能会出现暂时性的精液量减少、精子浓度降低、精子数量减少、精子活力降低、正常形态精子百分率降低及精子DNA碎片率增加等精液检测指标的变化,影响男性的精液质量、降低男性的生育能力,引发这一系列变化的机制可能包括了睾丸炎症、过度免疫、细胞因子风暴、内分泌功能受损和发热等,男性精液中是否存在新型冠状病毒还需要进一步的研究检测确定。综述新型冠状病毒感染对男性精液检测指标的具体影响和作用机制,为备孕期夫妇在感染新型冠状病毒后的相关治疗和辅助生殖治疗的受精时机选择提供参考。

At present,the mechanism of novel coronavirus infection has been clarified,and the male reproductive system may also be the target of novel coronavirus infection.After a man is infected with the novel coronavirus,there may be temporary decrease in semen volume,sperm concentration,sperm count,sperm motility,percentage of normal morphologic sperm,and increased sperm DNA fragment rate,and other semen detection indicators,which affect the quality of male semen and reduce male fertility.The possible mechanisms causing these changes include testicular inflammation,over-immunity,cytokine storm,the impaired endocrine function,fever,etc.Whether novel coronavirus exist in male semen needs further research and testing.In this paper,the specific effects of novel coronavirus infection on male semen indexes and the potential mechanism were summarized,providing a reference for pregnant couples to choose the fertilization time of related treatment and assisted reproductive treatment after their infection with novel coronavirus.