丁苯酞注射液联合阿司匹林和瑞舒伐他汀治疗老年脑梗死的疗效评价

Efficacy Evaluation of Butylphthalein Injection Combined with Aspirin and Rosuvastatin in the Treatment of Senile Cerebral Infarction

目的探究丁苯酞注射液联合阿司匹林和瑞舒伐他汀治疗老年脑梗死的临床疗效。方法选取我院2020年4月至2022年1月收治的100例老年脑梗死患者,使用随机数字法分为对照组(n=50)和观察组(n=50),对照组予以阿司匹林和瑞舒伐他汀治疗,观察组在对照组的基础上联合丁苯酞注射液治疗,对比两组患者治疗有效率、血黏度、神经功能缺损程度评分以及药物不良反应发生率。结果观察组治疗有效率94.00%高于对照组86.00%(P<0.05);治疗后,观察组患者血粘度、神经功能缺损程度(NIHSS)评分及药物不良反应发生率均低于对照组(P<0.05)。结论针对老年脑梗死患者采用丁苯酞注射液联合阿司匹林和瑞舒伐他汀治疗具有良好的效果,在提升临床疗效,降低患者血黏度和神经功能缺损程度,减少不良反应等方面具有积极意义。

Objective To explore the clinical efficacy of butylphthalein injection combined with aspirin and Rosuvastatin in the treatment of senile cerebral infarction.Method 100 elderly patients with cerebral infarction admitted to the hospital from April 2020 to January 2022 were selected and divided into control group(n=50)and observation group(n=50)by random number method.The control group was treated with aspirin and rosuvastatin,and the observation group was treated with butylphthalein injection on the basis of the control group.The treatment response rate,blood viscosity,neurological impairment and the incidence of adverse drug reactions were compared between the two groups.Results The effective rate of observation group was 94.00%higher than that of control group(86.00%)(P<0.05).After treatment,blood viscosity,neurological deficit(NIHSS)score and incidence of adverse drug reactions in observation group were lower than those in control group(P<0.05).Conclusion For elderly patients with cerebral infarction,the treatment of butylphthalein injection combined with aspirin and rosuvastatin has a good effect,which has positive significance in improving clinical efficacy,reducing patients'blood viscosity and neurological defects,and reducing adverse reactions.