尿微量白蛋白与尿肌酐比值在早期糖尿病肾病中的应用价值

Application Value of Urinary Microalbumin to Urinary Creatinine Ratio in Early Diabetic Nephropathy

目的 分析尿微量白蛋白与尿肌酐比值在早期糖尿病肾病诊断中的应用价值。方法 选择2019年10月—2022年10月将乐县总医院收治的98例糖尿病肾病患者中纳入观察组,且同期纳入健康体检人员98名为对照组。检测两组患者UMA、尿肌酐、血肌酐水平、ACR数值,比对两组观察组不同分期患者各指标水平。结果 观察组UMA、尿肌酐、ACR水平、血肌酐均较对照组高,差异有统计学意义(P<0.05);观察组Ⅰ期患者指标相比Ⅱ期、Ⅲ期、Ⅳ期患者指标水平均较低,且分期越高指标水平越高,差异有统计学意义(P<0.05)。结论 尿微量白蛋白与尿肌酐比值指标在糖尿病肾病早期诊断中具有较高的参考价值,可依据ACR指标水平评估患者病情,在后期治疗计划拟定和实施中提供指导价值,为后期相关研究提供参考。

Objective To analyze the diagnostic value of urinary microalbumin to urinary creatinine ratio In the early diagnosis of diabetic nephropathy.Methods 98 patients with diabetic nephropathy admitted to Jiangle General Hospital from October 2019 to October 2022 were included in the observation group,and 98 healthy examiner were included in the control group.The UMA,urinary creatinine,serum creatinine levels,ACR values were compared between the two groups and the patient observation group at different stages.Results The levels of UMA,urinary creatinine,ACR and serum creatinine in the observation group were higher than those in the control group,the difference was statistically significant(P<0.05).The indexes of patients in stage I of the observation group were lower than those in stage II,stage III and stage IV,and the higher the stage,the higher the index level,the difference was statistically significant(P<0.05).Conclusion The ratio index of urinary microalbumin to urinary creatinine has a high reference value in the early diagnosis of diabetic nephropathy,which can be used to evaluate patients´conditions according to the level of ACR index,provide guidance value in the formulation and implementation of later treatment plan,and provide reference for later related research.