视觉运动诱导的脑机接口技术应用于脑卒中患者上肢运动功能和认知功能的效果

Effect of visual motion-induced brain computer interface technology on upper limb motor and cognitive function of patients with stroke

目的探讨视觉运动诱导的脑机接口(BCI)技术应用于脑卒中患者上肢运动功能和认知功能的治疗效果。方法2021年7月至2022年3月,陕西省康复医院患有上肢手功能障碍和认知障碍的脑卒中患者50例随机分为对照组(n=25)和试验组(n=25)。两组均接受常规康复,对照组进行传统被动式手功能康复训练,试验组进行视觉运动诱导的BCI康复训练,共2周。治疗前后分别比较两组Fugl-Meyer评定量表上肢部分(FMAUE)、改良Barthel指数(MBI)和蒙特利尔认知评估量表(MoCA)评分,并对计算试验组的脑参与度。结果治疗前,两组FMA-UE、MBI和MoCA评分比较均无显著性差异(P>0.05)。治疗2周后,两组FMA-UE、MBI和MoCA评分均较治疗前显著提高(t>2.481,P<0.001),且试验组优于对照组(t>2.453,P<0.05);试验组平均脑参与度在治疗后上升21%。结论基于视觉运动诱导的BCI康复训练有利于促进脑卒中患者上肢运动功能的恢复以及认知功能的提升。

Objective To investigate the effects of visual motion-induced brain-computer interface(BCI)technology on upper limb motor function and cognitive function of patients with stroke.Methods From July,2021 to March,2022,50 stroke patients with upper limb hand dysfunction in Shaanxi Provincial Rehabilitation Hospital were randomly divided into control group(n=25)and experimental group(n=25).Both groups received conventional rehabilitation therapy,in addition,the control group received passive rehabilitation training,and the experimental group received visual motion-induced BCI rehabilitation training,for two weeks.They were assessed with Fugl-Meyer Assessment-Upper Extremities(FMA-UE),modified Barthel Index(MBI)and Montreal Cognitive Assessment(MoCA)before and after treatment.Brain participation was evaluated during the whole training process of the experimental group.Results Before treatment,there was no difference in the scores of FMA-UE,MBI and MoCA between two groups(P>0.05).Two weeks after treatment,the scores of FMA-UE,MBI and MoCA improved in both groups(t>2.481,P<0.001),and were better in the exprimental group than in the control group(t>2.453,P<0.05);the mean brain participation of the experimental group increased 21%after treatment.Conclusion Visual motion-induced BCI rehabilitation training could promote the recovery of motor function of upper limb,and cognitive function of patients with stroke.