我国中老年人正常体质量指数中心性肥胖与心血管危险因素及其聚集的关系

Relationship between Normal Weight Central Obesity and Cardiovascular Disease Risk Factors and Aggregation in Middle-aged and Elderly Chinese

目的探讨我国中老年人群正常体质量指数(BMI)中心性肥胖与心血管疾病危险因素及其聚集的关系,为心血管疾病防治提供科学依据。方法采用2015年中国健康与养老追踪调查(CHARLS)数据,共纳入5817例年龄45岁及以上且体质量正常的中老年人作为研究对象,分为正常体质量中心性肥胖(NWCO)组和正常体质量非中心性肥胖(NWNO)组,分析两组之间的差异,采用单因素和多因素Logistic回归分析中心性肥胖对高血压、糖尿病、血脂异常及其聚集的影响。结果我国中老年人NWCO检出率为40.2%。NWCO组高血压、糖尿病、血脂异常和危险因素聚集检出率均较NWNO组高(P均<0.01)。调整性别、年龄、婚姻状况、居住地区、文化程度、吸烟和饮酒情况后,NWCO组发生高血压、糖尿病、血脂异常和危险因素聚集的风险分别是NWNO组的1.651倍(OR=1.651,95%CI:1.461~1.865)、1.585倍(OR=1.585,95%CI:1.357~1.851)、1.900倍(OR=1.900,95%CI:1.686~2.143)和2.088倍(OR=2.088,95%CI:1.810~2.407)。结论我国中老年人NWCO检出率较高,NWCO是高血压、糖尿病、血脂异常及其聚集的危险因素,控制正常BMI中老年人群的腰围水平是预防心血管疾病的重要措施。

Objective To explore the relationship between central obesity and cardiovascular disease risk factors and aggregation in middle-aged and elderly people with normal body mass index(BMI)in China,so as to provide scientific basis for the prevention and treatment of cardiovascular diseases.Methods A total of 5817 middle-aged and elderly people who were aged 45 years and over with normal BMI from the China health and retirement longitudinal study(CHARLS)done in 2015.They were divided into two groups,normal weight central obesity(NWCO)group and normal weight no central obesity(NWNO)group.The differences between the two groups were analyzed.Logistic regression was used to do the multivariate analysis on the influence of central obesity on hypertension,diabetes mellitus,dyslipidemia,and aggregation.Results The prevalence of NWCO with middle-aged and elderly people was 40.2%in China.The prevalence rates of hypertension,diabetes,dyslipidemia and clustering of risk factors in NWCO group were higher than those in NWNO group(P all<0.01).After adjusting for gender,age,marital status,residential area,degree of education,smoking and drinking status,the risk of hypertension,diabetes,dyslipidemia and clustering of cardiovascular risk factors in the NWCO group was 1.651 times higher than that in the NWNO group(OR=1.651,95%CI:1.461-1.865),1.585 times(OR=1.585,95%CI:1.357-1.851),1.900 times(OR=1.900,95%CI:1.686-2.143)and 2.088 times(OR=2.088,95%CI:1.810-2.407),respectively.Conclusion The prevalence of NWCO is high in middle-aged and elderly people in China.NWCO is risk factor of cardiovascular disease risk factors and aggregation.It is important to control the level of waist circumference in middle-aged and elderly people with normal BMI to prevent cardiovascular diseases.