肌少症在乳腺癌患者中的研究进展

Advances in study of sarcopenia among patients with breast cancer

目的 总结肌少症在乳腺癌患者中的研究进展,以期为乳腺癌肌少症患者的治疗及预后提供新方向。方法 检索近年来国内外有关肌少症及乳腺癌的相关研究并进行综述。结果 肌少症在乳腺癌患者中发病率较高,且与乳腺癌患者的多种不良预后有关。运动、营养支持及药物辅助治疗可明显改善乳腺癌肌少症患者的生存质量。结论 肌少症作为乳腺癌的常见伴发疾病,严重影响患者的生存质量及预后。应密切监测乳腺癌患者肌少症的发生及发展,继续深入研究并明确其作用机制,以期发现新的治疗靶点。

Objective To explore the research progress of sarcopenia in breast cancer patients,with a view to providing new ideas for the treatment and prognosis of patients with sarcopenia in breast cancer.Method The literature relevant to studies on sarcopenia and breast cancer at home and abroad was searched and reviewed in recent years.Results Sarcopenia was highly prevalent in breast cancer patients and was associated with multiple poor prognoses in breast cancer patients.Exercise,nutritional support,and medication-assisted treatment could significantly improve the survival quality in breast cancer patients with sarcopenia.Conclusions As a common concomitant disease of breast cancer,sarcopenia seriously affects the survival quality and prognosis of patients.The development of sarcopenia in breast cancer patients should be closely monitored,and its mechanisms of action should continue to be studied and clarified in order to identify new therapeutic targets.