影像组学方法评价肝细胞癌微血管侵犯的研究进展

Research progress of radiomics in the evaluation of microvascular invasion in hepatocellular carcinoma

微血管侵犯(MVI)是肝细胞癌(HCC)切除术及移植术后早期复发和不良预后的独立预测因子。影像组学作为一种新颖的无创诊断工具,可以高通量提取肿瘤以及瘤周组织的定量成像特征,较视觉分析的常规及功能影像学提供更多的肿瘤异质性信息,在预测HCC患者是否存在MVI方面具有良好的应用前景,可以提高HCC诊断和预后的准确性。现结合最新的研究进展,阐述基于各种成像手段的多模态影像组学方法评估HCC患者存在MVI可能性的价值。

Microvascular invasion(MVI)is an independent predictor of early recurrence and poor prognosis following hepatocellular carcinoma(HCC)resection and transplantation.As a novel non-invasive diagnostic tool,radiomics can extract the quantitative imaging features of tumors and peritumoral tissues with high throughput,providing more information on tumor heterogeneity than conventional and functional imaging of visual analysis and having a good application prospect in predicting the presence of MVI in HCC patients,thereby improving the accuracy of HCC diagnosis and prognosis.The value of the multimodal radiomics method based on various imaging methods in evaluating the possibility of MVI in HCC patients is elucidated here in combination with the latest research progress.