预后准确性研究偏倚风险评价工具QUAPAS解读

An interpretation of QUAPAS:a tool for assessing risk of bias in prognostic accura studies

QUADAS-2、QUIPS和PROBAST工具并不针对预后准确性研究而开发,使用这些工具对预后准确性研究开展偏倚风险评价易导致偏差。近期国外研制了预后准确性研究的偏倚风险评价工具QUAPAS。该工具结合QUADAS-2、QUIPS和PROBAST,由5个领域、18个标志性问题、5个偏倚风险问题和4个适用性问题组成。本文对QUAPAS的内容和使用方法进行介绍,以期为国内研究者提供参考与借鉴。

The QUADAS-2,QUIPS,and PROBAST tools are not specific for prognostic accuracy studies and the use of these tools to assess the risk of bias in prognostic accuracy studies is prone to bias.Therefore,QUAPAS,a risk of bias assessment tool for prognostic accuracy studies,has recently been developed.The tool combines QUADAS-2,QUIPS,and PROBAST,and consists of 5 domains,18 signaling questions,5 risk of bias questions,and 4 applicability questions.This paper will introduce the content and usage of QUAPAS to provide inspiration and references for domestic researchers.