重视系统性红斑狼疮伴眼底损害与全身疾病的相关性

Pay attention to the association of systemic lupus erythematosus with ocular fundus impairment and systemic condition

系统性红斑狼疮(SLE)是一种累及全身多个系统的自身免疫性疾病,当眼底受累时,可能导致严重的视力损伤。近年来,"透过眼睛看健康"是一大研究热点。SLE的相关研究表明,视网膜病变与疾病活动度高度相关,在眼底尚未发生明确损害时,视网膜微血管密度和结构改变与SLE的病程、其他脏器受累也呈现出了一定的相关性。因此,对SLE患者的眼底特征进行评估,不仅有助于早期干预并改善患者的视功能预后,对SLE的诊断及其他系统损伤的预测也具有重要意义。

Systemic lupus erythematosus(SLE)is an autoimmune disease affecting multiple systems throughout the body,which may cause serious visual impairment when the fundus is involved.In recent years,"looking at health through the eyes"is a hot research topic.Studies on SLE have shown that retinopathy is highly correlated with disease activity.Even there is no clinical manifestation,changes in retinal microvessel density and structure also show a certain correlation with the course of SLE and other organs'involvement.Therefore,the evaluation of fundus features in SLE patients is not only helpful for early intervention and improvement of patients'visual function prognosis,but also of great significance for the diagnosis of SLE and prediction of other systems'impairment.