光学相干断层扫描成像在息肉样脉络膜血管病变临床诊疗中的应用和问题

Application and problems of optical coherence tomography in clinical diagnosis and treatment of polypoidal choroidal vasculopathy

息肉样脉络膜血管病变(PCV)是一种可造成严重视力损害的眼底疾病。目前诊断PCV的金标准是吲哚菁绿血管造影成像(ICGA),介于其有创性和临床应用的不便性,研究者正探索将无创的光学相干断层扫描(OCT)用于PCV的临床诊断和随访,也逐渐涌现了基于OCT的无创化诊断标准;但临床在应用该技术时,还存在成像效果不理想、诊断不明确、过度依赖OCT技术、随访情况复杂等问题。本文拟对OCT在PCV临床诊疗应用的现状、新的诊断标准和相关方面存在的问题进行述评,以期为眼科同道提供参考。

Polypoidal choroidal vasculopathy(PCV)is a fundus disease that can cause severe visual impairment.At present,the gold standard for the diagnosis of PCV is indocyanine green angiography(ICGA).Due to its invasiveness and inconvenience in clinical application,researchers are exploring the use of non-invasive optical coherence tomography(OCT)in clinical diagnosis and follow-up of PCV,and non-invasive diagnostic criteria based on OCT are gradually emerging.However,in the clinical application of this technology,there are still some problems,such as poor imaging effect,unclear diagnosis,over-reliance on OCT technology,complex follow-up situations and so on.This paper intends to review the current situation,new diagnostic criteria and related problems of OCT in the clinical diagnosis and treatment of PCV,in order to provide reference for ophthalmologists.