BUA、SOS、T-score和SI与老年女性膝骨关节炎患者骨密度的相关性及对骨质疏松的诊断效能

Correlation of BUA,SOS,T-score and SI with bone mineral density in elderly women with knee osteoarthritis and their diagnostic efficacy in osteoporosis

目的分析宽带超声振幅衰减(BUA)、超声传导速度(SOS)、骨密度标准差(T-score)和硬度指数(SI)指标与老年女性膝骨关节炎患者骨密度的相关性及对骨质疏松的诊断效能。方法选取2021年1月至2022年1月唐山市人民医院收治的50例老年女性膝骨关节炎患者作为观察组,另选同期女性体检健康人群40例为对照组。分析对比观察组和对照组BUA、SI、T-score及SOS的测定结果;比较不同年龄以及不同骨密度老年女性膝骨关节炎患者BUA、SI、T-score及SOS,并采用受试者工作特征(ROC)曲线分析BUA、SI、T-score及SOS对骨质疏松的诊断价值。结果观察组的BUA、SI、T-score均低于对照组,而SOS高于对照组(均P<0.05);不同年龄老年女性膝骨关节炎患者中,年龄越大,BUA、SI、T-score越低(均P<0.05),而不同年龄老年女性膝骨关节炎患者SOS比较差异无统计学意义(P>0.05)。不同骨密度分级老年女性膝骨关节炎患者中,骨质疏松组的BUA、SI、T-score均低于骨量减少组、骨质正常组,且骨量减少组低于骨质正常组,而SOS高于骨量减少组、骨质正常组,且骨量减少组高于骨质正常组(均P<0.05)。BUA、SOS、T-score和SI对诊断老年女性膝骨关节炎患者骨质疏松均具有较高的灵敏度、特异度(均P<0.05)。结论老年女性膝骨关节炎患者骨密度与BUA、SI、T-score和SOS相关,并且对骨质疏松具有较高的诊断价值。

Objective To analyze the broadband ultrasound attenuation(BUA),speed of sound(SOS),standard deviation of bone density(T-Score)and stiffness index(SI)with bone mineral density(BMD)in elderly female patients with knee osteoarthritis and their diagnostic efficacy of osteoporosis.Methods Fifty elderly female patients with knee osteoarthritis admitted o Tangshan People's Hospital from January 2021 to January 2022 were selected as the observation group,and 40 healthy female patients during the same period were selected as the control group.The results of BUA,SI,T-score and SOS in observation group and control group were analyzed and compared.The BUA,SI,T-score and SOS in elderly women with knee osteoarthritis at different ages and with different bone densities were compared,and the diagnostic value of BUA,SI,T-score and SOS in osteoporosis was analyzed by receiver operating characteristic(ROC)curve.Results The BUA,SI and T-score of observation group were lower than that in the control group,while SOS was higher than that in the control group(all P<0.05).Among elderly female patients with knee osteoarthritis of different ages,the older the age,the lower the BUA,SI and T-score(all P<0.05),while there was no statistical significance in SOS of elderly female patients with knee osteoarthritis of different ages(P>0.05).In elderly women with knee osteoarthritis with different BMD grades,the BUA,SI,and T-score in the osteoporosis group were lower than those in the osteopenia group and the normal bone group,and the BUA,SI,and T-score in the osteopenia group were lower than those in the normal bone group;the SOS in the osteoporosis group was higher than those in the osteopenia group and the normal bone group,and the SOS in the osteopenia group was higher than those in the normal bone group(all P<0.05).BUA,SOS,T-score and SI had high sensitivity and specificity in the diagnosis of osteoporosis in elderly women with knee osteoarthritis(all P<0.05).Conclusions BMD in elderly women with knee osteoarthritis is associated with BUA,SI,T-score,and SOS,and has high diagnostic value for osteoporosis.