盐酸左氧氟沙星治疗盆腔炎的效果分析

Effect Analysis of Levofloxacin Hydrochloride in Treatment of Pelvic Inflammatory Disease

目的:分析盐酸左氧氟沙星对盆腔炎患者临床症状、痊愈率及不良反应的影响。方法:选取2020年2月—2021年2月山东省东明县人民医院收治的80例盆腔炎患者为研究对象,依据用药方法分为盐酸左氧氟沙星组和氧氟沙星注射液组,各40例。分析两组症状、体征评分、疼痛程度、生活质量、临床疗效、症状缓解时间、用药时间、不良反应发生情况。结果:用药后,两组子宫及附件压痛、腹痛、白带增多、盆腔积液发生率低于用药前,盐酸左氧氟沙星组低于氧氟沙星注射液组,差异有统计学意义(P<0.05)。用药后,两组体征、疼痛评分低于用药前,盐酸左氧氟沙星组低于氧氟沙星注射液组,差异有统计学意义(P<0.05);两组生活质量评分均高于用药前,盐酸左氧氟沙星组高于氧氟沙星注射液组,差异有统计学意义(P<0.001)。盐酸左氧氟沙星组治疗总有效率高于氧氟沙星注射液组,差异有统计学意义(P=0.034)。盐酸左氧氟沙星组症状缓解时间、用药时间均短于氧氟沙星注射液组,差异有统计学意义(P<0.001)。盐酸左氧氟沙星组不良反应发生率低于氧氟沙星注射液组,差异有统计学意义(P=0.043)。结论:盐酸左氧氟沙星能有效缓解盆腔炎患者临床症状,提升治疗效果,降低不良反应发生率。

Objective:To analyze the effects of levofloxacin hydrochloride on clinical symptoms,recovery rate and adverse reactions in the patients with pelvic inflammatory disease.Methods:A total of 80 patients with pelvic inflammatory disease treated in Dongming County People's Hospital of Shandong Province from February 2020 to February 2021 were selected as the study subjects,and were divided into levofloxacin hydrochloride group and ofloxacin injection group according to medication methods,with 40 cases in each group.The score of symptoms and signs,pain degree,quality of life,clinical efficacy,symptom relief time,medication time and occurrence of adverse reactions in the two groups were analyzed.Results:After medication,the incidence of uterine and adnexal tenderness,abdominal pain,increased white vaginal discharge and pelvic effusion in the two groups was lower than that before medication,and the levofloxacin hydrochloride group was lower than the ofloxacin injection group,and the difference was statistically significant(P<0.05).After medication,the signs and pain scores in the two groups were lower than those before medication,and the levofloxacin hydrochloride group was lower than the ofloxacin injection group,and the difference was statistically significant(P<0.05).The quality of life scores in two groups were higher than those before medication,and the levofloxacin hydrochloride group was higher than the ofloxacin injection group,and the difference was statistically significant(P<0.001).The total effective rate of treatment in levofloxacin hydrochloride group was higher than that in ofloxacin injection group,and the difference was statistically significant(P=0.034).The symptom relief time and medication time in levofloxacin hydrochloride group were shorter than those in ofloxacin injection group,and the difference was statistically significant(P<0.001).The incidence of adverse reactions in levofloxacin hydrochloride group was lower than that in ofloxacin injection group,and the difference was statistically significant(P=0.043).Conclusion:Levofloxacin hydrochloride can effectively relieve the clinical symptoms of patients with pelvic inflammatory disease,improve the treatment effect,and reduce the incidence of adverse reactions.