多组分运动锻炼治疗老年慢性心力衰竭合并肌少症患者的临床效果

Clinical effect of multi-component exercise in the treatment of elderly patients with chronic heart failure complicated with sarcopenia

目的 观察多组分运动锻炼治疗老年慢性心力衰竭合并肌少症患者的临床效果。方法 采用便利抽样法选取96例老年慢性心力衰竭合并肌少症患者作为研究对象,按照入院先后顺序分为对照组和观察组,每组48例。对照组采用常规干预措施,观察组在常规干预措施基础上增加多组分运动锻炼,疗程均为12周。比较2组患者治疗前后的6 min步行试验(6MWT)距离、B型尿钠肽(BNP)水平、简易躯体功能评估工具(SPPB)评分、握力、生活自理能力(Barthel指数)评分。结果 治疗前,2组6MWT距离、BNP水平、SPPB评分、握力、Barthel指数评分比较,差异无统计学意义(P>0.05);治疗12周后,2组6MWT距离长于治疗前,BNP水平低于治疗前,SPPB评分、握力、Barthel指数评分高于治疗前,差异有统计学意义(P<0.05);治疗12周后,观察组6MWT距离长于对照组,BNP水平低于对照组,SPPB评分、握力、Barthel指数评分高于对照组,差异有统计学意义(P<0.05)。结论 多组分运动锻炼对老年慢性心力衰竭合并肌少症患者的治疗效果较好,可改善心功能,促进躯体功能恢复,提高患者生活自理能力。

Objective To observe the clinical effect of multi-component exercise in the elderly patients with chronic heart failure complicated with sarcopenia.Methods A total of 96 elderly patients with chronic heart failure complicated with sarcopenia were selected as research objects by convenient sampling method.They were divided into control group(n=48) and observation group(n=48) according to the order of admission.The control group received conventional intervention,while the observation group was supplemented with multi-component exercise on the basis of routine intervention.The treatment course was 12 weeks.Before and after treatment,6-minute walking test(6MWT),B-type urine natriuretic peptide(BNP),simple body function(SPPB),handhold strength and self-care ability(Barthel index) score in the two groups were analyzed and compared.Results Before treatment,there were no significant differences in 6MWT distance,BNP level,SPPB score,grip strength and Barthel index score between the two groups(P>0.05).After 12 weeks of treatment,the 6MWT distance of two groups was longer than before treatment,BNP level was lower than before treatment,SPPB score,grip strength and Barthel index score were higher than before treatment(P<0.05).After 12 weeks of treatment,the 6MWT distance of the observation group was longer than that of the control group,BNP level was lower than that of the control group,SPPB score,grip strength and Barthel index score were higher than that of the control group,the differences were statistically significant(P<0.05).Conclusion Multi-component exercise is effective in the treatment of elderly patients with chronic heart failure complicated with sarcopenia,which is helpful to improve heart function,promote the recovery of physical function,and improve the patients' self-care ability.