接骨七厘片(胶囊)治疗骨折临床应用专家共识

Expert consensus for Jiegu Qili Tablets(Capsules)in treatment of fracture in clinical practice

骨折是骨伤科临床最常见的疾病之一,接骨七厘片(胶囊)是临床常用于治疗骨折的国家医保目录甲类中成药,但至今尚无基于循证医学制订的共识或指南详细指导临床医生规范使用,严重制约了该药临床价值的发挥。该共识严格按照中成药临床应用专家共识步骤进行研制,以“循证为主、共识为辅、经验为鉴”的中成药推荐使用原则为指导思想,在文献梳理及问卷调研的基础上,及时总结现有接骨七厘片(胶囊)治疗骨折临床证据并吸纳临床专家经验,由全国27家中、西医医疗单位及科研机构多学科专家共同参与完成,编制过程历时1年余,于2021年9月由中华中医药学会正式发布(GS/CACM 293-2021)。该文详细介绍了共识制订的背景和目的,并阐述了立项、起草、专家共识、征求意见等主要编制过程,尤其针对接骨七厘片(胶囊)治疗骨折临床应用中的适应证、治疗时机、剂量、疗程及安全性等关键问题,形成了5条共识推荐意见和12条共识建议,旨在指导和规范临床医生合理使用,从而提高用药精准性和安全性。

Fracture is one of the common diseases in the department of orthopaedics and traumatology.Jiegu Qili Tablets(Capsules)are a Chinese patent medicine commonly used to treat fractures in clinical practice,which has been included in the Class A drugs of the catalog of medicines covered by the National Medical Insurance System.However,no consensus or guideline has yet been developed to guide clinicians based on an evidence-based approach in detail,which has severely limited the clinical value of this drug.According to the guiding principle of evidence as the key,consensus as the supplement,and experience as the reference,a consensus was developed in strict accordance with the steps stipulated in the expert consensus on clinical applications of proprietary Chinese medicines.Based on literature review and questionnaire survey,the consensus was a timely summary of the existing clinical evidence on the treatment of fractures with Jiegu Qili Tablets(Capsules),and incorporated the treatment experience of a number of clinical experts.The preparation process took more than a year and the consensus(GS/CACM 293-2021)was officially released by the China Association of Chinese Medicine in September 2021,with the participation of multidisciplinary experts from 27 organizations of Chinese and Western medicine and research institutions.This article introduces the background and objectives of the consensus in detail,and describes the main process of proposal,drafting,expert consensus,and consultation.In particular,5 consensusduration,and safety in the clinical application of Jiegu Qili Tablets ( Capsules) for the treatment of fractures,which guide andstandardize the rational use by clinicians and improve the accuracy and safety of drugs.