经阴道实时超声弹性成像与血清SCCA、CK19在鉴别诊断宫颈癌前病变及宫颈癌价值分析

Value of Transvaginal Real⁃time Ultrasonic Elastography Combined with Serum SCCA and CK19 Detection in Diagnosis of Cervical Precancerous Lesions and Cervical Cancer

目的分析经阴道实时超声弹性成像联合血清SCCA、CK19水平对宫颈癌前病变及宫颈癌的诊断。方法随机选择医院2019年1月至2021年1月诊治的宫颈癌前病变及宫颈癌患者各50例,均经病理证实,将其分成对常规组和研究组。采用经阴道实时超声弹性成像,检查两组血清SCCA、CK19水平。比较两组患者经阴道实时超声弹性成像评分和血清SCCA、CK19水平及阳性情况,分析联合诊断价值。结果研究组患者阴道实时超声弹性成像评分和血清SCCA、CK19水平均高于常规组(P<0.05)。研究组患者血清SCCA、CK19阳性率高于常规组(P<0.05)。经阴道实时超声弹性成像联合血清SCCA、CK19能提升宫颈癌前病变及宫颈癌的诊断价值(P<0.05)。结论经阴道实时超声弹性成像联合血清SCCA、CK19水平能提升对宫颈癌前病变及宫颈癌诊断价值,推荐使用。

Objective To investigate the value of transvaginal real⁃time ultrasonic elastography combined with serum SCCA and CK19 detection in diagnosis of cervical precancerous lesions and cervical cancer.Methods Patients with patho⁃logically confirmed cervical precancerous lesions and cervical cancer in our hospital from January 2019 to January 2021 were enrolled,and set as control group(n=50)and study group(n=50),respectively.All patients received transvaginal real⁃time ultrasonic elastography examination,and serum levels of SCCA and CK19 were also detected.The positive rate was compared among three examination methods,then the diagnostic value of combined detection was discussed.Results Real⁃time vagi⁃nal ultrasound elastographic scores and serum SCCA and CK19 levels were significantly higher in study group than in control group(P<0.05).The positivity rates of serum SCCA and CK19 were also significantly higher in study group than in control group(P<0.05).Transvaginal real⁃time ultrasound elastography combined with serum SCCA and CK19 detection could im⁃prove the diagnostic value of cervical precancerous lesions and cervical cancer(P<0.05).Conclusion Transvaginal real⁃time ultrasound elastography combined with serum SCCA and CK19 detection are of great significance in the clinical diagno⁃sis of cervical precancerous lesions and cervical cancer.