基于CiteSpace知识图谱的远志研究热点与前沿分析

CiteSpace knowledge map of research hotspots and frontiers of Polygalae Radix

该文全面检索Web of Science和中国知网(CNKI)关于中药远志的相关文献,经手动筛选最终纳入中文文献1207篇、英文文献263篇,采用Excel对远志研究年发文量绘制折线图,利用CiteSpace 6.1.R3文献计量学工具绘制远志研究的作者、机构、关键词共现、关键词聚类及关键词突现知识图谱。结果显示,远志研究的中、英文文献发文量均呈线性增长,且目前的研究热度不断攀升;王建、LIU X分别为中、英文发文量最多的作者;山西中医药大学和中国医学科学院分别为中、英文发文量最多的机构,且英文文献形成了以中国医学科学院为首的核心发文机构;中、英文关键词分析显示远志研究的热点集中在品种选育、药材质量标准、有效化学成分提取及鉴定、方剂配伍、中药炮制、临床用药规律、药理作用机制等方面,其中远志及其含有远志的相关临床制剂有效成分对脑神经保护作用、受体通路调节、抗焦虑、改善阿尔茨海默病的作用机制,数据挖掘及临床用药规律是其前沿方向。该研究为今后远志研究的选题和前沿识别具有一定的借鉴意义。

In this study,the Web of Science and China National Knowledge Infrastructure(CNKI)were searched comprehensively for the literature about the research on Polygalae Radix.After manual screening,1207 Chinese articles and 263 English articles were included in this study.Excel was used to draw the line chart of the annual number of relevant publications.CiteSpace 6.1.R3 was used for the visual analysis of author cooperation,publishing institutions,keyword co-occurrence,keyword clustering,and bursts in the research on Polygalae Radix.The results showed that the number of articles published in Chinese and English increased linearly,which indicated the rising research popularity of Polygalae Radix.WANG J and LIU X were the authors publishing the most articles in Chinese and English,respectively.Shanxi University of Chinese Medicine and Chinese Academy of Medical Sciences were the research institutions with the largest number of Chinese and English publications in this field,respectively.The institutions publishing the relevant articles in English formed a system with the Chinese Academy of Medical Sciences as the core.According to the keywords,the research hotspots of Polygalae Radix included variety selection and breeding,quality standard,extraction and identification of active chemical components,prescription compatibility,processing,clinical medication rules,and pharmacological mechanism.The research frontiers were the molecular mechanisms of Polygalae Radix and its active components in exerting the protective effect on brain nerve,regulating receptor pathways,alleviating anxiety and Alzheimer′s disease,as well as data mining and clinical medication summary.This study has reference significance for the topic selection and frontier identification of the future research on Polygalae Radix.