提高对血管内治疗后迟发性非缺血性脑增强病变的认识

Strengthening the understanding of delayed onset of non-ischemic cerebral enhancing lesions after endovascular therapy

迟发性非缺血性脑增强(NICE)病变是颅内血管内治疗(EVT)后,尤其是动脉瘤栓塞术后的一种罕见并发症,主要累及EVT远端流域,具有复杂且较一致的影像学特征,临床表现多样,预后良好,但诊断困难,目前尚无统一的诊断治疗标准。该文阐述迟发性NICE病变的流行病学、发病机制、病理特征、临床影像特点及诊断治疗,以提高对该病的诊疗水平。

Delayed onset of non-ischemic cerebral enhancing(NICE)lesions is a rare complication after endovascular therapy(EVT),especially after aneurysm embolization.The lesions are mainly distributed in the vascular regions distal to EVT.Delayed onset of NICE lesions exhibit complicated and homogenous imaging features with diverse clinical manifestations and good prognosis.However,it is difficult to be diagnosed and there has been no consensus on diagnostic and therapeutic strategies.This article describes the epidemiology,pathogenesis,pathological features,clinical and imaging characteristics,diagnosis and treatment of delayed onset of NICE lesions,so as to facilitate the diagnosis and treatment of the disease.