XPS表面分析技术在生物医用金属材料研究中的应用

Application of XPS surface analysis technique in the research of biomedical metallic materials

利用先进表征技术对生物医用金属材料的表面性质进行分析,并揭示其表界面与机体的相互作用机理至关重要。X射线光电子能谱(X-ray photoelectron spectroscopy,XPS)作为一种强有力的表面分析技术,可以高灵敏度、高分辨率地对材料表面元素种类和价态进行定性、半定量分析,并能结合离子束溅射、角分辨深度剖析获得材料表面层的纵深分布信息,已被广泛应用于生物医用金属材料研究。基于此,首先介绍了XPS的原理和特点;其次,根据生物医用金属材料的分类和研究领域,重点探讨了XPS表面分析技术在医用不锈钢、医用钴基合金、医用钛及其合金、医用镁合金的设计制造、表面改性及表界面表征等方面的应用;再次,通过总结上述工作的优势与不足,进一步阐明了XPS表面分析技术在小面积、化学成像、角分辨、原位测试、价带谱、同步辐射激发源等多种功能方面的应用潜力;最后,对XPS技术助力新型生物医用金属材料的开发和应用提出了展望和建议。

Because the surface properties of biomedical metallic materials determine their biological properties,it is very important to elucidate the physical and chemical properties of biomedical metallic materials and to reveal the interaction mechanisms between the surface interface and the body through advanced characterization techniques.X-ray photoelectron spectroscopy(XPS)is a powerful surface analysis technique which can be used for qualitative and semi-quantitative analysis of elements and valence states on material surface with high sensitivity and resolution.Combined with ion beam sputtering and angular resolution depth analysis,the depth distribution information of the surface layer can be obtained.XPS surface analysis technique has been widely used in the research of biomedical metallic materials.In this paper,firstly,the principle and characteristics of XPS are briefly introduced.Secondly,according to the classification and research field of biomedical metallic materials,the application of XPS surface analysis technique in the design,manufacture,surface modification and surface interface characterization of biomedical stainless steel,biomedical cobalt-based alloys,biomedical titanium alloys and biomedical magnesium alloys are mainly discussed.By summarizing the advantages and disadvantages of the above work,it further clarifies the application potential of XPS surface analysis technique in small area,chemical imaging,angle resolution,in-situ testing,valence band spectrum,synchrotron radiation excitation source and other aspects.Finally,the prospect and suggestions for the development and application of new biomedical metallic materials assisted by XPS technique are put forward.