摘要
趋化因子受体3(CXCR3),一种表达在T细胞上的G蛋白偶联受体,可由趋化因子激活,在免疫和炎症中起着重要的作用。研究表明,CXCR3及其配体参与了多种不同病因的心血管疾病,包括动脉粥样硬化、高血压、心肌梗死、心肌炎、心力衰竭。本文旨在总结趋化因子在心血管疾病中的研究进展。
Chemokine receptor 3(CXCR3),a G protein-coupled receptor expressed on T cells that can be activated by chemokines,plays an important role in immunity and inflammation.Studies have shown that CXCR3 and its ligands are involved in cardiovascular diseases of various etiologies,including atherosclerosis,hypertension,myocardial infarction,myocarditis,and heart failure.This review aims to summarize the research progress of chemokines in cardiovascular diseases.
作者
曾康
杨滨
曹慧丽
赵娅敬
李松珊
温泽宇
代虎威
ZENG Kang;YANG Bin;CAO Hui-li;ZHAO Ya-jing;LI Song-shan;WEN Ze-yu;DAI Hu-wei(Department of Second Clinical Medicine,Shanxi Medical University,Taiyuan 030000,China;Department of Cardiovascular Medicine,the Second Hospital of Shanxi Medical University,Taiyuan 030000,China)
出处
《中国心血管病研究》
CAS
2023年第5期452-457,共6页
Chinese Journal of Cardiovascular Research
基金
山西省自然科学研究面上项目(20210302123289)。
