原发性肺黏液腺癌文献复习并3例报道

Primary mucinous adenocarcinoma of the lung:three cases report and literature review

目的 分析原发性肺黏液腺癌(primary pulmonary mucinous adenocarcinoma, PPMA)的临床表现、影像学特征、病理特点、治疗等,提高临床对该病的认识。方法 选择2022年6月至2022年10月收治的3例原发性肺黏液腺癌的临床诊治经过,3例为女性,年龄73~85岁,为高龄。结合文献复习,提高对原发性肺黏液腺癌临床表现、影像学特征、病理特点等认识,提高诊断及治疗水平。结果 原发性肺黏液腺癌以浸润性黏液腺癌为主,临床表现无特异性,易被误诊,诊断主要依靠病理,治疗以早期手术为主。结论 原发性肺黏液腺癌是肺腺癌的一种特殊亚型,临床诊断缺乏特异性,诊断主要依赖活组织病理。

Objective To investigate the clinical manifestations,imaging features and pathological characteristics of primary pulmonary mucinous adenocarcinoma(PPMA)and improve the understanding of the disease.Methods Through the clinical diagnosis and treatment of 3 cases of primary mucinous lung adenocarcinoma from June 2022 to October 2022 was analyzed.All of them were female,aged 73 to 85 old.Combined with literature analysis and literature review,to strengthen clinicians′understanding of the clinical manifestations,imaging characteristics and pathological characteristics of this disease,improve the level of diagnosis and treatment.Results The primary mucinous adenocarcinoma of the lung was mainly invasive mucinous adenocarcinoma.The clinical manifestations were not specific,and it was easy to be misdiagnosed.The diagnosis mainly depended on pathology,and the treatment was mainly early operation.Conclusion PPMA is a special subtype of lung adenocarcinoma with low incidence and poor prognosis.The lack of specificity in clinical diagnosis mainly depends on biopsy.