恶性肿瘤患者营养不良诊断标准研究进展

Research progress on GLIM criteria for malnutrition in patients with malignant tumors

营养不良是恶性肿瘤患者的常见合并症,影响肿瘤患者的临床结局,准确识别营养不良是营养干预治疗的前提,但目前缺乏统一的营养不良诊断标准。随着2018年全球营养专家发起的营养不良诊断标准(GLIM)的正式发布,大量研究随之开展。本文主要对GLIM的具体内容和争议,及在恶性肿瘤患者特别是放疗患者中的准确性验证和临床预测价值进行综述,为今后恶性肿瘤相关的营养不良研究及临床应用提供参考。

Malnutrition is a common complication in patients with malignant tumors,which affects the clinical outcome of cancer patients.Accurate identification of malnutrition is the premise of nutritional intervention and treatment,but uniform diagnostic criteria for malnutrition are currently lacking.With the official release of the Global Leadership Initiative on Malnutrition(GLIM)initiated by global nutrition experts in 2018,a large cohort of studies have been carried out.In this article,the specific content and controversies of the GLIM criteria,its accuracy validation and clinical predictive value in patients with malignant tumors were mainly reviewed,aiming to provide reference for subsequent research and clinical application of malignant tumor-related malnutrition.