摘要
帕金森病是常见的神经系统退行性疾病,具有高度的临床异质性。随着精准医疗概念的提出,国内外学者应用多组学技术、生物信息技术和分子影像技术,对帕金森病的病理机制、临床分型、诊断和治疗进行了大量研究。文中将对帕金森病精准诊疗的现况及发展方向进行阐述。
Parkinson′s disease is a common neurodegenerative disease with high clinical heterogeneity.With the development of precision medicine,numerous researches have been conducted on the pathological mechanism,clinical classification,diagnosis and treatment of Parkinson′s disease through multi-omics,bioformatics and molecular imaging.This article will elaborate the current practice and future research directions of precision medicine in the diagnosis and treatment of Parkinson′s disease.
作者
王诗婵
商慧芳
Wang Shichan;Shang Huifang(Department of Neurology,West China Hospital,Sichuan University,Chengdu 610041,China)
出处
《中华神经科杂志》
CAS
CSCD
北大核心
2023年第5期469-475,共7页
Chinese Journal of Neurology
基金
四川省科技计划项目(2022ZDZX0023)。
关键词
帕金森病
精准医疗
基因组学
Parkinson disease
Precision medicine
Genomics