光催化[2+1+2]串联反应合成二氢咪唑及其机理探究

Photocatalytic[2+1+2]Tandem Reactions for the Synthesis of Dihydroimidazole and Its Mechanism Study

将光催化领域前沿研究——可见光氧化还原催化引入到有机化学实验教学中,拓展学生的光化学反应、多组分催化串联反应、自由基化学等知识,加深学生对亲核反应机理和离子型中间体的认识。实验由咪唑啉类化合物的制备、反应机理探究和实验拓展三部分组成,涉及无水无氧等多种有机化学实验操作及反应监测、分离纯化、产物表征等。

The introduction of the frontier research in the photocatalysis field is important in the teaching of organic chemistry laboratory.It not only expands students’knowledge of photochemical,multi-component catalytic cascade and free radical reactions,but also deepen students’understanding of nucleophilic reaction mechanism and radical and ionic intermediates.The experiment involves three parts:product preparation,mechanism exploration and experimental expansion of imidazoline compounds,including various organic experimental operations such as anhydrous and anaerobic,reaction monitoring,separation,purification and product characterization.