舒糖络方治疗痰瘀阻络型糖尿病周围神经病变的临床观察

Clinical observation of Shutangluo recipe in the treatment of patients with diabetic peripheral neuropathy of phlegm-stasis blocking collateral type

目的:观察舒糖络方治疗痰瘀阻络型糖尿病周围神经病变(DPN)的临床效果。方法:将60例DPN患者随机分为观察组和对照组,每组30例。对照组给予硫辛酸片联合依帕司他片口服治疗,观察组在对照组治疗的基础上予舒糖络方治疗,两组均治疗8周。比较两组患者的临床治疗效果,治疗前后中医证候积分,腓总神经和正中神经的运动神经、感觉神经传导速度。结果:观察组总有效率为93.33%高于对照组73.33%,差异有统计学意义(P<0.05)。治疗后,两组中医证候积分,腓总神经和正中神经的运动神经、感觉神经传导速度情况均改善,且观察组的改善幅度更明显(P<0.05)。结论:舒糖络方能够显著提高痰瘀阻络型DPN患者的临床疗效,改善中医证候及神经功能,值得临床推广应用。

Objective:To observe the clinical efficacy of Shutangluo recipe in the treatment of patients with diabetic peripheral neuropathy(DPN)of phlegm-stasis blocking collateral type.Methods:60 cases of DPN patients were randomly divided into the observation group and control group,each with 30 cases.The control group were given oral treatment with thioctic acid tablets combined with epalrestat tablets,while the observation group were given Shutangluo recipe on the basis of the treatment for the control group.Both groups were treated for 8 weeks.The clinical efficacy,TCM syndrome scores,the motor and sensory nerve conduction velocity of the common peroneal nerve and the median nerve before and after treatment were compared between the two groups.Results:The total effective rate of the observation group was 93.33%,which was higher than 73.33%of the control group,the difference was statistically significant(P<0.05).After treatment,TCM syndrome scores,the motor and sensory nerve conduction velocity of the common peroneal nerve and the median nerve were improved in both groups,and the improvement in the observation group was more obvious(P<0.05).Conclusion:Shutangluo recipe can significantly improve the clinical efficacy,TCM syndromes and neurological function of DPN patients with phlegm-stasis blocking collateral type,which is worthy of clinical application.