早期运动康复治疗联合新活素对急性心肌梗死急诊PCI术后运动耐力及心功能的影响

Effect of Early Exercise Rehabilitation Therapy Combined with Neoxin on Exercise Endurance and Cardiac Function After Emergency PCI for Acute Myocardial Infarction

目的探讨早期运动康复治疗联合新活素在急性心肌梗死(AMI)患者行急诊经皮冠状动脉介入(PCI)术后的应用效果。方法按随机数表法将2021年1~12月于本院行急诊PCI手术的100例AMI患者分为两组,每组50例。两组均实施新活素静脉治疗,对照组实施常规康复指导,观察组在对照组基础上实施早期运动康复治疗,两组均干预3个月。比较两组运动耐力、心功能水平、心理状况、生活质量和不良事件的发生情况。结果干预后,观察组6 min步行试验(6 MWT)距离长于对照组(P<0.05);观察组左室舒张末容积(LVEDV)和左室收缩末期内径(LVESD)水平低于对照组,左心室射血分数(LVEF)水平高于对照组(P<0.05);观察组焦虑自评量表(SAS)和抑郁自评量表(SDS)评分低于对照组(P<0.05);观察组生活质量量表(SF-36)评分高于对照组(P<0.05);观察组不良事件总发生率为4.00%(2/50),低于对照组的16.00%(8/50)(P<0.05)。结论AMI患者行急诊PCI术后应用早期运动康复治疗联合新活素,利于提高运动耐力和心功能水平,改善不良情绪,减少不良事件的发生,进而提高生活质量。

Objective To investigate the application effect of early exercise rehabilitation therapy combined with neoxin in patients with acute myocardial infarction(AMI)after emergency percutaneous coronary intervention(PCI).Methods A total of 100 patients with AMI who underwent emergency PCI in our hospital from January 2021 to December 2021 were divided into two groups by random number table method,with 50 patients in each group.Patients in both groups were treated with intravenous neoactive therapy,the control group was treated with routine rehabilitation guidance,and the observation group was treated with early exercise rehabilitation on the basis of the control group.Both groups were treated with intervention for 3 months.Exercise endurance,cardiac function,psychological status,quality of life and adverse events were compared between the two groups.Results After intervention,the 6MWT distance of observation group was longer than that of control group(P<0.05).After intervention,the levels of left ventricular end-diastolic volume(LVEDV)and left ventricular end-systolic inner diameter(LVESD)in observation group were lower than those in control group,and left ventricular ejection fraction(LVEF)was higher than that in control group(P<0.05).After intervention,the scores of self-rating Anxiety Scale(SAS)and Self-rating Depression Scale(SDS)in observation group were lower than those in control group(P<0.05);After intervention,the score of SF-36 in observation group was higher than that in control group(P<0.05).After intervention,the total incidence of adverse events in the observation group was 4.00%,which was lower than that in the control group(16.00%,P<0.05).Conclusion The application of early exercise rehabilitation therapy combined with neoxin after emergency PCI in AMI patients is beneficial to improve exercise endurance and cardiac function level,improve adverse mood,reduce the overall incidence of adverse events,and improve the quality of life.