6~13岁儿童慢性呼吸系统疾病阻塞性肺功能损害危险因素分析

Analysis of risk factors for obstructive pulmonary function impairment in children aged 6~13 years old with chronic respiratory diseases

目的:分析6~13岁儿童慢性呼吸系统疾病阻塞性肺功能损害的相关危险因素。方法:选取2022年1月—12月接诊的86例6~13岁儿童慢性呼吸系统疾病患者,按照患者是否出现了阻塞性肺功能损害将其划分成对照组(n=45)及观察组(n=41)。对照组患者未出现阻塞性肺功能损害,观察组患者出现了阻塞性肺功能损害,结合患者的情况对导致患者出现阻塞性肺功能损害的相关危险因素进行探讨。采用多因素Logistic回归模型分析,患者年龄、身高、体重、临床资料等相关因素对儿童慢性呼吸系统疾病阻塞性肺功能损害的相关危险因素进行分析。结果:在年龄、身高、体重方面,两组患者无显著统计学差异;从观察组患者的情况来看,患者过敏原IgE检测阳性、既往存在过敏性鼻炎、严重肺疾病病史等方面所占比例高于对照组。多因素Logistic回归模型分析显示,过敏原IgE检测阳性、既往存在过敏性鼻炎、严重肺疾病病史是导致患者在呼吸系统疾病的基础上出现阻塞性肺功能损害的危险因素(P<0.05)。结论:6~13岁儿童慢性呼吸系统疾病阻塞性肺功能损害相关危险因素主要包括患者过敏原IgE检测阳性、既往存在过敏性鼻炎、严重肺疾病病史等几个方面,如果慢性呼吸系统疾病的患者,存在以上几个方面的问题,则需警惕出现阻塞性肺功能损害的可能。

Objective To analyse the relevant risk factors of obstructive pulmonary function impairment in children aged 6 to 13 years old with chronic respiratory diseases.Methods 86 children aged 6 to 13 with chronic respiratory diseases admitted from January to December 2022 were selected as the study subjects.They were divided into a control group(n=45)and an observation group(n=41)based on whether the patients had obstructive pulmonary function impairment.The control group patients did not experience obstructive pulmonary function damage,while the observation group patients experienced obstructive pulmonary function damage.Based on the patient’s situation,discussion was conducted on the relevant risk factors leading to obstructive pulmonary function damage in patients.Using a multivariate logistic regression model analysis,analysis was conducted on the risk factors of obstructive pulmonary function impairment in children with chronic respiratory disease,including patient age,height,weight,and clinical data.Result There was no significant statistical difference between the two groups of patients in terms of age,height,and weight;From the situation of the observation group patients,the overall probability of positive allergen IgE testing,past history of allergic rhinitis,and severe lung disease in the patients were higher than those in the control group.Multivariate logistic regression model analysis showed that positive allergen IgE testing,previous allergic rhinitis,and a history of severe lung disease were risk factors for patients with obstructive pulmonary function damage on the basis of respiratory diseases(P<0.05).Conclusion The risk factors related to obstructive pulmonary function impairment in children aged 6 to 13 years old with chronic respiratory diseases mainly include positive allergen IgE testing,previous history of allergic rhinitis,and a history of severe lung disease.If patients with chronic respiratory diseases have problems in the above aspects,they should be vigilant about the possibility of obstructive pulmonary function impairment.