孕晚期妊娠期糖尿病患者发生抑郁的影响因素

Influencing factors of depression in patients with gestational diabetes mellitus in late pregnancy

目的:分析孕晚期妊娠期糖尿病(GDM)患者发生抑郁的影响因素。方法:选取2019年5月至2022年3月该院收治的107例孕晚期GDM患者进行横断面研究,观察孕晚期GDM患者抑郁发生率,将抑郁自评量表(SDS)评分≥53分者纳入发生组,SDS评分<53分者纳入未发生组,比较两组临床资料,采用多因素Logistic回归分析孕晚期GDM患者发生抑郁的影响因素。结果:孕晚期GDM患者抑郁发生率为55.14%(59/107);发生组空腹血糖(FPG)水平、非计划妊娠占比、孕前未服用叶酸占比、不良孕史占比均高于未发生组,社会支持评定量表(SSRS)评分低于未发生组,差异有统计学意义(P<0.05);Logistic回归分析结果显示,FPG水平≥7.06 mmol/L、非计划妊娠、孕前未服用叶酸、有不良孕史和SSRS评分<27.91分均为孕晚期GDM患者发生抑郁的危险因素(OR>1,P<0.05)。结论:FPG水平≥7.06 mmol/L、非计划妊娠、孕前未服用叶酸、有不良孕史和SSRS评分<27.91分均为孕晚期GDM患者发生抑郁的危险因素。

Objective:To analyze influencing factors of depression in patients with gestational diabetes mellitus(GDM)in late pregnancy.Methods:A cross-sectional study was conducted on 107 patients with GDM in the late pregnancy admitted to the hospital from May 2019 to March 2022.The incidence of depression in these GDM patients was observed.The patients with self-rating depression scale(SDS)score≥53 were included in occurrence group,and those with SDS score<53 were included in non-occurrence group.The clinical data of the two groups were compared.Multivariate logistic regression analysis was used to analyze the influencing factors of depression in the GDM patients in the late pregnancy.Results:The incidence of depression in the patients with GDM in the late pregnancy was 55.14%(59/107).The FPG level,the proportion of unplanned pregnancy,the proportion of not taking folic acid before pregnancy and the proportion of adverse pregnancy history in the occurrence group were higher than those in the non-occurrence group;the SSRS score was lower than that of the non-occurrence group;and the differences were statistically significant(P<0.05).Logistic regression analysis showed that FPG level≥7.06 mmol/L,unplanned pregnancy,not taking folic acid before pregnancy,adverse pregnancy history and SSRS score<27.91 were risk factors for depression in the GDM patients in the late pregnancy(OR>1,P<0.05).Conclusions:FPG level≥7.06 mmol/L,unplanned pregnancy,not taking folic acid before pregnancy,adverse pregnancy history and SSRS score<27.91 are the risk factors for depression in the GDM patients in the late pregnancy。