无痛胃肠镜患者丙泊酚复合舒芬太尼麻醉效果及麻醉复苏情况分析

Analysis of the Effect of Propofol Compounded with Sufentanil Anesthesia and Anesthetic Resuscitation in Patients Undergoing Painless Gastroenteroscopy

目的:探讨丙泊酚复合舒芬太尼对无痛胃肠镜患者麻醉效果和麻醉复苏的影响。方法:选取本院2020年3月至2021年11月138例择期行无痛胃肠镜患者,通过随机数字表法简单随机分为观察组和对照组,每组69例患者,观察组应用丙泊酚复合舒芬太尼,对照组应用丙泊酚,比较两组血流动力学、药物用量、认知功能。结果:两组麻醉优良率比较(P>0.05);两组麻醉入睡后平均动脉压(MAP)、心率(HR)较麻醉前降低,在胃镜检查中、肠镜检查中MAP、HR水平又出现升高,但仍低于麻醉前(P<0.05);观察组胃镜、肠镜检查MAP、HR低于对照组(P<0.05);两组麻醉后血氧饱和度(SpO 2)水平比较(P>0.05);观察组较对照组丙泊酚药物用量,检查后恢复时间短(P<0.05);观察组检查后30min简易智力状态检测量表(MMSE)评分低于对照组(P<0.05);两组检查后1h、3h MMSE评分比较(P>0.05);两组不良反应发生率比较(P>0.05)。结论:无痛胃肠镜患者应用丙泊酚复合舒芬太尼,操作中血液循环稳定,丙泊酚药物用量减少,检查完成后麻醉恢复快。

Objective:To investigate the effect of propofol compounded with sufentanil on anesthetic efficacy and anesthetic resuscitation in patients undergoing painless gastroenteroscopy.Methods:A total of 138 patients who were waiting to undergo painless gastroscopy in our hospital from March 2020 to November 2021 were selected and simply randomly divided into observation and control groups by random number table method,69 patients in each group.The observation group was given propofol compounded with sufentanil and the control group was given propofol.The hemodynamics,drug dosage and cognitive function were compared between the two groups.Results:There was no significant difference in good rate of anesthesia between the two groups(P>0.05).After anesthesia,mean arterial pressure(MAP)and heart rate(HR)were lower than those before anesthesia in both groups.MAP and HR were increased during gastroscopy and endoscopy,still lower than those before anesthesia(P<0.05).During gastroscopy and endoscopy,MAP and HR were lower in observation group than control group(P<0.05).After anesthesia,there was no significant difference in blood oxygen saturation(SpO2)between the two groups(P>0.05).The dosage of propofol was smaller in observation group than control group,and recovery time after examination was shorter in observation group(P<0.05).At 30 min after examination,score of mini-mental state examination(MMSE)was lower in observation group than control group(P<0.05).There was no significant difference in MMSE scores between the two groups at 1h and 3h after after examination(P>0.05).The difference in incidence of adverse reactions between the two groups was not statistically significant(P>0.05).Conclusion:The application of propofol compounded with sufentanil in patients undergoing painless gastroenteroscopy resulted in stable blood circulation during the operation,reduced dosage of propofol drug,and rapid recovery from anesthesia after completion of the examination.